Microreaction and membrane technologies for continuous single-enantiomer production: A review
نویسندگان
چکیده
Microreaction and membrane technologies offer optimal conditions for controlling enantiomer synthesis purification processes in continuous production, with numerous advantages over batch manufacturing. One of the many forces driving development such production single optical isomers is need enantiomerically pure pharmaceutical drugs because enantiomers may display opposite therapeutic effects or different treatment efficacies side effects. Yet, despite advances asymmetric separation techniques, preparing compounds remains a challenging task. Here, we review progress microfluidics chiral last two decades. In addition to describing critically assessing state art both disciplines, provide an overview their beneficial properties characteristics developing toward producing compounds. Concomitantly, evaluate efforts integrate into microfluidic platform pinpoint limiting factors that must be overcome before these platforms can fully deployed industry.
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ژورنال
عنوان ژورنال: Catalysis Reviews-science and Engineering
سال: 2021
ISSN: ['0161-4940', '1520-5703']
DOI: https://doi.org/10.1080/01614940.2021.1977009